Diagnostic pitfalls of neonatal herpes infection

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Neonatal herpes simplex infection.

Tremendous advances have occurred over the past 30 years in the diagnosis and management of neonatal herpes simplex virus (HSV) disease. Mortality in patients with disseminated disease has decreased from 85 to 29%, and that in patients with central nervous system (CNS) disease has decreased from 50 to 4%. Morbidity has been improved more modestly: the proportion of patients with disseminated di...

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Neonatal urological ultrasound: diagnostic inaccuracies and pitfalls.

Ninety one patients with urinary tract abnormalities diagnosed before birth were reviewed. Diagnoses based on prenatal and postnatal ultrasound scans alone were compared with the final diagnoses after full urological investigations, with operative or necropsy confirmation in 79 cases. The results confirmed that ultrasound examination before birth usually detects nonspecific abnormalities and al...

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Neonatal herpes simplex virus infection

Neonatal herpes simplex virus (HSV) infections may be caused by either herpes simplex virus type-1 (HSV-1) or herpes simplex virus type-2 (HSV-2). In the United States, HSV-2 is responsible for 75% of genital and neonatal infections, while HSV-1 causes the rest. HSV-1 more commonly affects the oropharynx, the eyes and the central nervous system.1,2 It is estimated that 20 to 30% of sexually act...

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Antiviral prophylaxis of neonatal herpes infection.

Herpes simplex virus (HSV) is considered to be one of the most frequent viral infectious agents in humans. Transmission of HSV from mother to foetus during pregnancy is uncommon with about 85% of transmission occurring perinatally, when neonates acquire HSV during vaginal birth from infected genital tract secretions. For women, who present with an episode of recurrent genital herpes several wee...

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Relapse of neonatal herpes simplex virus infection.

BACKGROUND Neonatal herpes simplex virus (HSV) infection is a severe disease with high mortality and morbidity. Recurrence of skin vesicles is common. OBJECTIVE To determine the features of relapse and identify the factors related to relapse. DESIGN Thirty two surviving patients with neonatal herpes virus infections were enrolled. All patients received acyclovir treatment. Clinical and viro...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology

سال: 2016

ISSN: 0019-5154

DOI: 10.4103/0019-5154.174140